Isa 10:5 O Assyrian, the rod of mine anger, and the staff in their hand is mine indignation.
I don't see Reuben, Asher, Zebulun, Naphtali, Gad, Issachar or Dan in this end time confederation. They, along with Judah, Benjamin and Levi, are going to be corrected by Assyria. It makes a lot of sense that the King of the South (Islamic confederacy) will push at the reorganized Europe and Europe will come down in that area and crush them. I don't see this Islamic confederacy being much more than a flash in the pan and then fading into insignificance...
Dan 11:40 And at the time of the end shall the king of the south push at him: and the king of the north shall come against him like a whirlwind, with chariots, and with horsemen, and with many ships; and he shall enter into the countries, and shall overflow and pass over.
Dan 11:41 He shall enter also into the glorious land, and many countries shall be overthrown: but these shall escape out of his hand, even Edom, and Moab, and the chief of the children of Ammon.
Isa 16:1-4, Isa 33:14-19, Psalm 91 The place of safety in Southern Jordan?
Dan 11:42 He shall stretch forth his hand also upon the countries: and the land of Egypt shall not escape.
Dan 11:43 But he shall have power over the treasures of gold and of silver, and over all the precious things of Egypt: and the Libyans and the Ethiopians shall be at his steps.
Some other translations have it as a whipped dog at his heels.